Today’s Best Bets: 04-25-08

Global Endeavors Benefit concert
9 p.m., 40 Watt

Local favorites Modern Skirts will perform to benefit Global Endeavors’s trip to Ghana this summer to help build a medical clinic. The band’s indie pop sound often draws comparisons to the Beach Boys’ harmonies and Ben Folds Five’s piano-driven rock. Nashville-based pop rock band Pico Vs. Island Trees and The Bridges, a female-fronted pop rock band that will appeal to fans of Rilo Kiley, will also perform. Tickets are $8 to $10. - Trisha Klein

Old Crow Medicine Show
9 p.m. today-Saturday, Georgia Theatre

This Nashville, Tenn.-based, American roots band is best known for its performances on A Prairie Home Companion with Garrison Keillor, but the members are younger and hipper than that association would lead you to believe. Tickets are $20 per night or $35 for a two-day pass. - Trisha Klein

Cinemechanica, HO-AG, Bad Dudes, Mouser
10 p.m., Caledonia Lounge

Local label Hello Sir Records presents two local bands and two out-of-towners. A local favorite, Cinemechanica rocks twice as hard with dueling guitars. Adding moog synths and a theremin to the usual suspects of guitars, bass and drums, Boston’s HO-AG plays moody, spazz rock. Los Angeles-based Bad Dudes play energetic math rock. Mouser is a large, loud, experimental rock band with fast drums and blaring horns. Admission is $6 to 7. - Trisha Klein